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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: TSGRLSFTVR SLLDLPEQDA QHLPRREPEP RAPQPDPCAA WLDSERGHYP SSDESSLETS PPDSSQR
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 69%.
A murine NKX2-8 was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor. Nkx2.8 bound to the active AFP promoter, and antisense inhibition of Nkx2.8 mRNA translation selectively reduced expression of both the endogenous human AFP gene and transfected reporters containing the rat AFP promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Homeobox protein NK-2 homolog H; Homeobox protein Nkx-2.8
Gene Aliases: NKX-2.8; NKX2-8; NKX2G; NKX2H
Entrez Gene ID: (Human) 26257
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