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          • Primary Antibodies ›
          • EML4 Antibodies

          Invitrogen

          EML4 Polyclonal Antibody

          Advanced Verification
          View all (12) EML4 antibodies

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          Cite EML4 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (8)
          • Advanced Verification (1)
          EML4 Antibody in Immunohistochemistry (IHC)
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          EML4 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 9

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          EML4 Antibody (PA5-64218) in IHC

          Immunohistochemical staining of EML4 in human cerebral cortex, gallbladder, kidney and lymph node using EML4 Polyclonal Antibody (Product # PA5-64218) (A) shows similar protein distribution across tissues to an independent EML4 Polyclonal Antibody (B). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          EML4 Antibody in Immunohistochemistry (IHC)
          EML4 Antibody in Immunohistochemistry (IHC)
          EML4 Antibody in Immunohistochemistry (IHC)
          EML4 Antibody in Immunohistochemistry (IHC)
          EML4 Antibody in Immunohistochemistry (IHC)
          EML4 Antibody in Immunohistochemistry (IHC)
          EML4 Antibody in Immunohistochemistry (IHC)
          EML4 Antibody in Western Blot (WB)
          EML4 Antibody
          EML4 Polyclonal Antibody

          Product Details

          PA5-64218

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:2,500-1:5,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human EML4. Recombinant protein control fragment (Product #RP-103598).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Amount

          30 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2641023

          Product Specific Information

          Immunogen sequence: GGVMLIWSKT TVEPTPGKGP KGVYQISKQI KAHDGSVFTL CQMRNGMLLT GGGKDRKIIL WDHDLNPERE IEVPDQYGTI

          Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 95%.

          Target Information

          Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT, interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: echinoderm microtubule associated protein like 4; Echinoderm microtubule-associated protein-like 4; EMAP-4; EML4/ALK fusion protein; OTTHUMP00000201447; OTTHUMP00000201455; Restrictedly overexpressed proliferation-associated protein; Ropp 120; unnamed protein product

          View more View less

          Gene Aliases: C2orf2; ELP120; EMAP-4; EMAPL4; EML4; ROPP120

          View more View less

          UniProt ID: (Human) Q9HC35

          View more View less

          Entrez Gene ID: (Human) 27436

          View more View less

          Function(s)
          protein binding microtubule binding alpha-tubulin binding beta-tubulin binding
          Process(es)
          microtubule cytoskeleton organization mitotic cell cycle microtubule-based process mitotic metaphase plate congression attachment of spindle microtubules to kinetochore cell division
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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