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Invitrogen
YME1L1 Polyclonal Antibody
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Product Details
PA5-64299
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human YME1L1. Recombinant protein control fragment (Product #RP-103788).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AVDGKEMVTM KELEFSKDKI LMGPERRSVE IDNKNKTITA YHESGHAIIA YYTKDAMPIN KATIMPRGPT LGHVSLLPEN DRWNETRAQL LAQMDVS
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent metalloprotease FtsH1; ATP-dependent metalloprotease FtsH1 homolog; ATP-dependent zinc metalloprotease YME1L1; Meg-4; PAMP; Presenilin-associated metalloprotease; unnamed protein product; YME1-like protein 1
Gene Aliases: FTSH; FTSH1; MEG4; OPA11; PAMP; UNQ1868/PRO4304; YME1L; YME1L1
UniProt ID: (Human) Q96TA2
Entrez Gene ID: (Human) 10730
proteolysis
misfolded or incompletely synthesized protein catabolic process
mitochondrion organization
cell proliferation
cellular response to starvation
positive regulation of mitochondrial fusion
protein hexamerization
mitochondrial protein processing
mitochondrial protein catabolic process
negative regulation of apoptotic process
neuronal stem cell population maintenance
regulation of stem cell division
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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