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          • Primary Antibodies ›
          • MMP27 Antibodies

          Invitrogen

          MMP27 Polyclonal Antibody

          View all (5) MMP27 antibodies

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          Cite MMP27 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          MMP27 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          MMP27 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          MMP27 Antibody (PA5-64398) in IHC (P)

          Immunohistochemical analysis of MMP27 in human bronchus using MMP27 Polyclonal Antibody (Product # PA5-64398) shows moderate positivity in cilia of respiratory epithelia cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MMP27 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MMP27 Polyclonal Antibody

          Product Details

          PA5-64398

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000-1:2,500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human MMP27. Recombinant protein control fragment (Product #RP-104100).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.4 mg/mL

          Amount

          40 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2644015

          Product Specific Information

          Immunogen sequence: FWPSLPADLQ AAYENPRDKI LVFKDENFWM IRGYAVLPDY PKSIHTLGFP GRVKKIDAAV CDKTTR

          Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 83%.

          Target Information

          Metalloproteinases (MMPs) are a family of proteins that are involved in the breakdown of the extracellular matrix during normal cellular events, including reproduction, tissue remodeling and embryonic development. MMPs are crucial in tumor invasion and building of metastatic formations because of their ability to degrade extracellular matrix proteins such as fibronectin, laminin, gelatins and/or collagen. MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein that is expressed in B-cells. Belonging to the peptidase M10A family, MMP-27 contains four hemopexin-like domains, which is suggested to be involved in substrate recognition. MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: matrix metallo protease; matrix metalloprotease 27; Matrix metalloproteinase-27; MMP; MMP-27; MMPs

          View more View less

          Gene Aliases: MMP-27; MMP27; UNQ2503/PRO5992

          View more View less

          UniProt ID: (Human) Q9H306

          View more View less

          Entrez Gene ID: (Human) 64066

          View more View less

          Function(s)
          metalloendopeptidase activity peptidase activity metallopeptidase activity zinc ion binding hydrolase activity metal ion binding
          Process(es)
          proteolysis extracellular matrix organization collagen catabolic process
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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