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Invitrogen
HSPBP1 Polyclonal Antibody
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Product Details
PA5-64461
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HSPBP1. Recombinant protein control fragment (Product #RP-103930).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KLKVKSAFLL QNLLVGHPEH KGTLCSMGMV QQLVALVRTE HSPFHEHVLG ALCSLVTDFP QGVRECREPE LGLEELLRHR CQLLQQHEEY QEELEFCEKL LQT
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.
Target Information
HspBP1 is an Hsp70-interacting protein that was first isolated from a human heart cDNA library using the yeast two-hybrid system. The ATPase domain of Hsp70 binds HspBP1 and upon binding, inhibits Hsp70 chaperone activity. More recently HspBP1 was found to promote nucleotide dissociation from Hsc70 (3) and is capable of altering the confirmation of the Hsp70 ATPase domain. HspBP1 is capable of regulating any Hsp70 activity that requires ATPase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Heat shock protein; Heat shock protein-binding protein 1; HSP; hsp70 interacting protein; Hsp70-binding protein 1; Hsp70-binding protein 2; Hsp70-interacting protein 1; Hsp70-interacting protein 2; HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1; HspBP1; HspBP2
Gene Aliases: FES1; HSPBP; HSPBP1; PP1845
UniProt ID: (Human) Q9NZL4
Entrez Gene ID: (Human) 23640
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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