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Invitrogen
EYA1 Polyclonal Antibody
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Product Details
PA5-65034
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human EYA1. Recombinant protein control fragment (Product #RP-105800).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SQSPGQTGFLS YGTSFSTPQP GQAPYSYQMQ GSSFTTSSGI YTGNNSLTNS SGFNSSQQDY PSYPSFGQGQ YAQYYNSSPY PAHYMTSSNT SPTTPSTNAT YQLQEPPSGI TSQAVTDPTA EYSTIHSPST PIKDSDSDRL RRGSD
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 97%.
Target Information
This gene encodes a member of the eyes absent family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EYA1B; EYA1C; Eyes absent; Eyes absent homolog 1; MGC141875; OTTHUMP00000195053; Protein phosphatase EYA1; unnamed protein product
Gene Aliases: BOP; BOR; BOS1; EYA1; OFC1; OTFCS
UniProt ID: (Human) Q99502
Entrez Gene ID: (Human) 2138
metanephros development
ureteric bud development
branching involved in ureteric bud morphogenesis
outflow tract morphogenesis
DNA repair
double-strand break repair
chromatin organization
chromatin remodeling
cellular response to DNA damage stimulus
pattern specification process
mesodermal cell fate specification
sensory perception of sound
anatomical structure morphogenesis
organ morphogenesis
response to ionizing radiation
striated muscle tissue development
protein sumoylation
cell differentiation
aorta morphogenesis
inner ear morphogenesis
outer ear morphogenesis
middle ear morphogenesis
cell fate commitment
regulation of neuron differentiation
positive regulation of DNA repair
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
neuron fate specification
embryonic skeletal system morphogenesis
semicircular canal morphogenesis
epithelial cell proliferation
positive regulation of epithelial cell proliferation
pharyngeal system development
otic vesicle development
otic vesicle morphogenesis
positive regulation of secondary heart field cardioblast proliferation
cochlea morphogenesis
extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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