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Invitrogen
RAD52 Polyclonal Antibody
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Product Details
PA5-65036
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human RAD52. Recombinant protein control fragment (Product #RP-105801).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ILGGRDSHPAA GGGSVLCFGQ CQYTAEEYQA IQKALRQRLG PEYISSRMAG GGQKVCYIEG HRVINLANEM FGYNGWAHSI TQQNVDFVDL NNGKFYVGVC AFVRVQLKDG SYHEDVGYGV SE
Highest antigen sequence identity to the following orthologs - mouse 90%, rat 90%.
Target Information
DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which includeRAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DNA repair protein RAD52 homolog; homologue of yeast DNA repair and recombination enzyme (RAD52) gene; hypothetical; recombination protein RAD52; rhabdomyosarcoma antigen MU-RMS-40.23; unnamed protein product
Gene Aliases: RAD52
UniProt ID: (Human) P43351
Entrez Gene ID: (Human) 5893
double-strand break repair via homologous recombination
DNA recombinase assembly
DNA repair
double-strand break repair
DNA recombination
mitotic recombination
cellular response to DNA damage stimulus
DNA double-strand break processing involved in repair via single-strand annealing
cellular response to oxidative stress
double-strand break repair via single-strand annealing
regulation of nucleotide-excision repair
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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