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Invitrogen
HUS1B Polyclonal Antibody
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Product Details
PA5-65122
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human HUS1B. Recombinant protein control fragment (Product #RP-105886).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GASSLKLQLTH KRRPSLTVAV ELVSSLGRAR SVVHDLPVRV LPRRVWRDCL PPSLRASDAS IRLPRWRTLR SIVERMANVG SHVL
Highest antigen sequence identity to the following orthologs - mouse 67%, rat 66%.
Target Information
HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Checkpoint protein HUS1B; hHUS1B; HUS1 checkpoint homolog b; MGC126746; MGC126748; RP11-532F6.1
Gene Aliases: HUS1B
UniProt ID: (Human) Q8NHY5
Entrez Gene ID: (Human) 135458
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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