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Invitrogen
Adenylate Cyclase 7 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-65289
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Adenylate Cyclase 7. Recombinant protein control fragment (Product #RP-98571).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PFAHLNHRESV SSGETHVPNG RRPKSVPQRH RRTPDRSMSP KGRSEDDSYD DEMLSAIEGL SSTRPCCSKS DDFYTFGSIF L
Highest antigen sequence identity to the following orthologs - mouse 79%, rat 79%.
Target Information
This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adenylate cyclase type VII; adenylyl cyclase 7; ATP pyrophosphate-lyase 7; cyclic di-AMP synthase ADCY7; FLJ36387; KIAA0037; unnamed protein product
Gene Aliases: AC7
UniProt ID: (Human) P51828
Entrez Gene ID: (Human) 113
regulation of adaptive immune response
renal water homeostasis
cAMP biosynthetic process
adenylate cyclase-activating G-protein coupled receptor signaling pathway
cyclic nucleotide biosynthetic process
positive regulation of toll-like receptor 9 signaling pathway
intracellular signal transduction
maternal process involved in female pregnancy
cellular response to lithium ion
cellular response to ethanol
cellular response to glucagon stimulus
vascular endothelial cell response to laminar fluid shear stress
negative regulation of cytokine production involved in inflammatory response
positive regulation of NLRP3 inflammasome complex assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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