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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: VNQAVSPNFSQ GSAIIIASPV QPVLQGMVGM IPVSVVGQNG NNFSTPPRQV LHMPLTAPVC NRSIPQFPVP PKSQKAQGLR NKPCIGKQVN NLVDSSGHSV
Highest antigen sequence identity to the following orthologs - mouse 83%, rat 85%.
Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Nuclear protein of the ataxia telangiectasia mutated locus; Nuclear protein of the ATM locus; p220; Protein NPAT
Gene Aliases: CAND3; E14; NPAT
Entrez Gene ID: (Human) 4863
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