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Invitrogen
DUSP18 Polyclonal Antibody
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Product Details
PA5-65657
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human DUSP18. Recombinant protein control fragment (Product #RP-106334).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: APSCAFPVQFR QPSVSGLSQI TKSLYISNGV AATN
Highest antigen sequence identity to the following orthologs - mouse 74%, rat 71%.
Target Information
DUSP18 (E.C 3.1.3.16), a novel DSP, is a member of highly conserved protein-tyrosine phosphatase super family. Members of this family cooperate with protein kinases and play a vital role in cell cycle regulation and mitogenic signal transduction. DUSP18 is a low molecular weight protein consisting of conserved N-terminal DSP domain but lacks CH2 domain. Studies reveal that DUSP18 is a unique DSP that interacts and dephosphorylates SAPK/JNK. Reports suggest it inhibits SAPK/JNK invivo and might serve an important role in the regulation of SAPK/JNK pathway. Northern Blot analysis detected a ubiquitous expression of DUSP18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bK963H5.1; Dual specificity protein phosphatase 18; LMW-DSP20; Low molecular weight dual specificity phosphatase 20; unnamed protein product
Gene Aliases: DSP18; DUSP18; DUSP20; LMWDSP20
UniProt ID: (Human) Q8NEJ0
Entrez Gene ID: (Human) 150290
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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