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Invitrogen
NME7 Polyclonal Antibody
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Product Details
PA5-65852
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human NME7. Recombinant protein control fragment (Product #RP-106521).
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SIRALFGTDGI RNAAHGPDSF ASAAREMELF FPSSGGCGPA NTAKFTNCTC CIVKPHAVSE GLLGKILMAI RDAGFEISAM QMFNMDRVN
Highest antigen sequence identity to the following orthologs - mouse 87%, rat 88%.
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3'-5' exonuclease NME7; cilia and flagella associated protein 67; NDK 7; NDP kinase 7; nm23-H7; non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase); Nucleoside diphosphate kinase homolog 7; nucleoside-diphosphate kinase 7; Protein kinase NME7
Gene Aliases: CFAP67; MN23H7; NDK 7; NDK7; nm23-H7; NME7
UniProt ID: (Human) Q9Y5B8
Entrez Gene ID: (Human) 29922
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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