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Invitrogen
AGL Polyclonal Antibody
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Product Details
PA5-65863
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human AGL. Recombinant protein control fragment (Product #RP-106531).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LAKCLGPFDEW ESRLRVAKES GYNMIHFTPL QTLGLSRSCY SLANQLELNP DFSRPNRKYT WNDVGQLVEK LKKEWNVICI TDVVYNHTAA NSKWIQEHPE
Highest antigen sequence identity to the following orthologs - mouse 90%, rat 92%.
Target Information
This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-Apr; 4-glucantransferase; amylo-1, 6-glucosidase, 4-alpha-glucanotransferase; amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase; amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferaseprovided; Glycogen debrancher; Glycogen debranching enzyme; glycogen debranching protein; Oligo-1
Gene Aliases: AGL; GDE
UniProt ID: (Human) P35573
Entrez Gene ID: (Human) 178
catalytic activity
4-alpha-glucanotransferase activity
amylo-alpha-1,6-glucosidase activity
protein binding
transferase activity
transferase activity, transferring glycosyl groups
hydrolase activity
hydrolase activity, acting on glycosyl bonds
carbohydrate binding
polysaccharide binding
polyubiquitin binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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