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Invitrogen
Neuropilin 2 Polyclonal Antibody
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Product Details
PA5-65910
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Neuropilin 2. Recombinant protein control fragment (Product #RP-105007).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PSGFNCNFDFL EEPCGWMYDH AKWLRTTWAS SSSPNDRTFP DDRNFLRLQS DSQREGQYAR LISPPVHLPR SPVCMEFQY
Highest antigen sequence identity to the following orthologs - mouse 85%, rat 83%.
Target Information
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C) and SEMA3F protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F), and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Neuropilin-2; neuropilin-2a(17); neuropilin-2a(22); neuropilin-2b(0); receptor for VEGF165 and semaphorins class 3; receptor for VEGF165 and semaphorins class3; unnamed protein product; Vascular endothelial cell growth factor 165 receptor 2
Gene Aliases: NP2; NPN2; NRP2; PRO2714; VEGF165R2
UniProt ID: (Human) O60462
Entrez Gene ID: (Human) 8828
angiogenesis
neuron migration
positive regulation of endothelial cell proliferation
outflow tract septum morphogenesis
cell adhesion
nervous system development
axon guidance
heart development
positive regulation of endothelial cell migration
facial nerve structural organization
trigeminal nerve structural organization
vestibulocochlear nerve structural organization
nerve development
branchiomotor neuron axon guidance
gonadotrophin-releasing hormone neuronal migration to the hypothalamus
cell differentiation
trunk neural crest cell migration
ventral trunk neural crest cell migration
vascular endothelial growth factor signaling pathway
axon extension involved in axon guidance
negative chemotaxis
sympathetic ganglion development
trigeminal ganglion development
semaphorin-plexin signaling pathway
sensory neuron axon guidance
sympathetic neuron projection extension
sympathetic neuron projection guidance
regulation of postsynapse organization
neural crest cell migration involved in autonomic nervous system development
facioacoustic ganglion development
dorsal root ganglion morphogenesis
cellular response to leukemia inhibitory factor
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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