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Invitrogen
ZGPAT Polyclonal Antibody
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Product Details
PA5-66034
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human ZGPAT. Recombinant protein control fragment (Product #RP-105049).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ALCPSLAVVGS DAVDSGTCSS AFAGWEVHTR GIGSRLLTKM GYEFGKGLGR HAEGRVEPIH AVVLPRGKSL DQCVETLQKQ TRVG
Highest antigen sequence identity to the following orthologs - mouse 78%, rat 78%.
Target Information
Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G patch domain-containing protein 6; unnamed protein product; Zinc finger and G patch domain-containing protein; Zinc finger CCCH domain-containing protein 9; Zinc finger CCCH-type with G patch domain-containing protein; zinc finger, CCCH-type with G patch domain
Gene Aliases: GPATC6; GPATCH6; KIAA1847; ZC3H9; ZC3HDC9; ZGPAT; ZIP
UniProt ID: (Human) Q8N5A5
Entrez Gene ID: (Human) 84619
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
nucleic acid binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
zinc ion binding
sequence-specific DNA binding
metal ion binding
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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