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Invitrogen
HOXD13 Polyclonal Antibody
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Product Details
PA5-66661
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human HOXD13. Recombinant protein control fragment (Product #RP-107309).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SFYQGYTSPYQ HVPGYIDMVS TFGSGEPRHE AYISMEGYQS WTLANGWNSQ VYCTKDQPQG SHFWKSSFPG
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.
Target Information
HOXD13 (homeobox protein D13) belongs to a class of transcription factors called homeobox proteins. In vertebrates, homeobox are found in clusters called A, B, C, and D on four separate chromosomes. Expression of homeobox proteins is spatially and temporally regulated during embryonic development. The gene encoding HOXD13 is part of the D cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in the HOXD13 gene cause synpolydactyly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: homeo box 4I; homeo box D13; Homeobox protein Hox-4I; Homeobox protein Hox-D13
Gene Aliases: BDE; BDSD; HOX4I; HOXD13; SPD; SPD1
UniProt ID: (Human) P35453
Entrez Gene ID: (Human) 3239
skeletal system development
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
anterior/posterior pattern specification
male genitalia development
regulation of cell proliferation
embryonic digit morphogenesis
positive regulation of transcription from RNA polymerase II promoter
embryonic hindgut morphogenesis
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
morphogenesis of an epithelial fold
branch elongation of an epithelium
regulation of branching involved in prostate gland morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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