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Invitrogen
MOZ Polyclonal Antibody
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Product Details
PA5-66742
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
C. elegans,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human MOZ. Recombinant protein control fragment (Product #RP-107398).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KELEEQPTRED VKEEPGVQES FLDANMQKSR EKIKDKEETE LDSEEEQPSH DTSVVSEQMA GSEDDHEEDS HTKE
Highest antigen sequence identity to the following orthologs - mouse 75%, rat 73%.
Target Information
Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Histone acetyltransferase KAT6A; histone acetyltransferase MYST3; K(lysine) acetyltransferase 6A; Monocytic leukemia zinc finger protein; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; MYST histone acetyltransferase (monocytic leukemia) 3; MYST-3; runt-related transcription factor binding protein 2; Runt-related transcription factor-binding protein 2; Zinc finger protein 220
Gene Aliases: KAT6A; MOZ; MRD32; MYST-3; MYST3; RUNXBP2; ZC2HC6A; ZNF220
UniProt ID: (Human) Q92794
Entrez Gene ID: (Human) 7994
DNA packaging
nucleosome assembly
transcription, DNA-templated
protein acetylation
histone acetylation
myeloid cell differentiation
histone H3 acetylation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
cellular senescence
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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