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Invitrogen
ATP5J2 Polyclonal Antibody
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Product Details
PA5-66906
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human ATP5J2. Recombinant protein control fragment (Product #RP-107559).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FGAFQRGYYRY YNKYINVKK
Highest antigen sequence identity to the following orthologs - mouse 80%, rat 80%.
Target Information
The ATP5MF gene encodes the ATP synthase membrane subunit F, which is a part of the mitochondrial ATP synthase complex (Complex V). This complex plays a crucial role in the process of oxidative phosphorylation, where ADP is converted to ATP, the primary energy currency of the cell. The ATP synthase complex consists of two main domains: the F1 catalytic core and the F0 proton channel. ATP5MF is a component of the F0 domain, helping to form the membrane channel that facilitates proton translocation across the mitochondrial membrane. This proton translocation is essential for driving the synthesis of ATP. Mutations or dysfunction in the ATP5MF gene can lead to mitochondrial disorders, which can have significant implications for cellular energy production and are associated with various metabolic and neurodegenerative diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP synthase f chain, mitochondrial; ATP synthase F(0) complex subunit f, mitochondrial; ATP synthase membrane subunit f; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f; ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2; ATP5J2; F1F0-type ATPase subunit f; F1Fo-ATP synthase complex Fo membrane domain f subunit; F1Fo-ATPase synthase f subunit
Gene Aliases: ATP5J2; ATP5JL; ATP5MF
UniProt ID: (Human) P56134
Entrez Gene ID: (Human) 9551
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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