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Invitrogen
ANKH Polyclonal Antibody
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Product Details
PA5-66977
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human ANKH. Recombinant protein control fragment (Product #RP-107620).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ACYVYRKQKKK MENESATEGE DSAMTDMPPT EEVTDIVEMR EENE
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 98%.
Target Information
ANKH is a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANK; ankylosis, progressive homolog; ATP carrier protein ANKH; FLJ27166; Mineralization regulator ANKH; Progressive ankylosis protein homolog; solute carrier family 62, member 1; unnamed protein product
Gene Aliases: ANK; ANKH; CCAL2; CMDJ; CPPDD; HANK; KIAA1581; MANK; SLC62A1; UNQ241/PRO274
UniProt ID: (Human) Q9HCJ1
Entrez Gene ID: (Human) 56172
skeletal system development
locomotory behavior
gene expression
bone mineralization
regulation of bone mineralization
inorganic diphosphate transport
phosphate ion transmembrane transport
muscle cell cellular homeostasis
phosphate ion homeostasis
calcium ion homeostasis
transmembrane transport
diphosphate metabolic process
cementum mineralization
inhibition of non-skeletal tissue mineralization
response to sodium phosphate
ATP export
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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