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Invitrogen
SNW1 Polyclonal Antibody
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Product Details
PA5-82017
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SNW1. Recombinant protein control fragment (Product #RP-88945).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RNLSRAAPDK RSKLQRNENR DISEVIALGV PNPRTSNEVQ YDQRLFNQSK GMDSGFAGGE DEIYNVYDQA WRGGKDMAQS IYRPSKNLDK DMYGDDLEAR IKTNRFVPDK EFSGSDRRQR GREGPVQFEE DPFGLDKF
Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 98%.
Target Information
CSTF2 is one of three (including CSTF1 and CSTF3) cleavage stimulation factors which combine to form CSTF which is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. CSTF2 contains a ribonucleoprotein-type RNA binding domain. CSTF2 is upregulated during activation of B cells which results in the switch of IgM heavy chain mRNA from membrane bound form to the secreted form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homolog of Drosophila BX42; Nuclear protein SkiP; Nuclear receptor coactivator NCoA-62; nuclear receptor coactivator, 62-kD; PPS; SKI interacting protein; SKI-interacting protein; SNW domain-containing protein 1
Gene Aliases: 2310008B08Rik; AW048543; Bx42; NCOA-62; Prp45; PRPF45; RGD1561926; SKIIP; SKIP; SNW1
UniProt ID: (Human) Q13573, (Mouse) Q9CSN1
Entrez Gene ID: (Human) 22938, (Mouse) 66354, (Rat) 500695
transcription coactivator activity
transcription corepressor activity
Notch binding
protein binding
nuclear hormone receptor binding
vitamin D receptor binding
retinoic acid receptor binding
poly(A) RNA binding
SMAD binding
RNA metabolism protein
RNA processing factor
RNA splicing factor
nucleic acid metabolism protein
negative regulation of transcription from RNA polymerase II promoter
mRNA splicing, via spliceosome
regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
Notch signaling pathway
viral process
positive regulation of transforming growth factor beta receptor signaling pathway
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation by host of viral transcription
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of mRNA splicing, via spliceosome
retinoic acid receptor signaling pathway
regulation of retinoic acid receptor signaling pathway
positive regulation of neurogenesis
positive regulation of histone H3-K4 methylation
regulation of vitamin D receptor signaling pathway
positive regulation of vitamin D receptor signaling pathway
cellular response to retinoic acid
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
RNA splicing
skeletal muscle cell differentiation
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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