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Invitrogen
RSK4 Polyclonal Antibody
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Product Details
PA5-82038
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RPS6KA6. Recombinant protein control fragment (Product #RP-92168).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PFKPASGKPD DTFCFDPEFT AKTPKDSPGL PASANAHQLF KGFSFVATSI AEEYKITPIT SANVLPIVQI NGNAAQFGEV YELKEDIGVG SYSVCKRCIH ATTNMEFAVK IIDKSK
Highest antigen sequence indentity to the following orthologs: Mouse - 91%, Rat - 91%.
Target Information
RPS6KA6 (RSK4) is a member of the RSK kinases family. RSK family members are activated by ERKs and mitogens and are unusual in that they contain 2 non-identical kinase domains. RSK4 encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 90 kDa ribosomal protein S6 kinase 6; p90-RSK 6; pp90RSK4; Ribosomal protein S6 kinase alpha-6; ribosomal protein S6 kinase, 90kDa, polypeptide 6; Ribosomal S6 kinase 4; RPS6KA6; RSK-4; S6K-alpha 6; S6K-alpha-6; S6KA6; unnamed protein product
Gene Aliases: p90RSK6; PP90RSK4; RPS6KA6; RSK-4; RSK4; S6K-alpha-6
UniProt ID: (Human) Q9UK32
Entrez Gene ID: (Human) 27330
signal transduction
central nervous system development
DNA damage response, signal transduction by p53 class mediator
intracellular signal transduction
TORC1 signaling
negative regulation of embryonic development
negative regulation of ERK1 and ERK2 cascade
negative regulation of mesoderm development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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