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Invitrogen
SETD3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-82105
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SETD3. Recombinant protein control fragment (Product #RP-89073).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ERASPNSFWQ PYIQTLPSEY DTPLYFEEDE VRYLQSTQAI HDVFSQYKNT ARQYAYFYKV IQTHPHANKL PLKDSFTYED YRWAVSSVMT RQNQIPTEDG SR
Highest antigen sequence indentity to the following orthologs: Rat - 98%, Mouse - 97%.
Target Information
SETD3 is a histone methyltransferase that is involved in epigenetic transcriptional activation by methylating lysine residues on histone H3 tails.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: endothelial differentiation inhibitory protein D10; histone-lysine N-methyltransferase setd3; histone-lysine N-methyltransferase setd3-like; protein-L-histidine N-tele-methyltransferase; SET domain containing 3, actin histidine methyltransferase; SET domain-containing protein 3; unnamed protein product
Gene Aliases: 2610102I01Rik; 2610305M23Rik; 6030490B17Rik; C14orf154; D12Ertd771e; hSETD3; RGD1309550
UniProt ID: (Human) Q86TU7, (Mouse) Q91WC0, (Rat) G3V6U9
Entrez Gene ID: (Human) 84193, (Mouse) 52690, (Rat) 299295
transcription coactivator activity
protein binding
protein-lysine N-methyltransferase activity
protein-histidine N-methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
histone methyltransferase activity (H3-K36 specific)
RNA polymerase II sequence-specific DNA binding transcription factor binding
chromatin remodeling
actin filament organization
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of uterine smooth muscle contraction
peptidyl-histidine methylation
actin modification
positive regulation of muscle cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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