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Invitrogen
Laminin beta-1 Polyclonal Antibody
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Product Details
PA5-82138
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LAMB1. Recombinant protein control fragment (Product #RP-102389).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NQVVSLSPGS RYVVLPRPVC FEKGTNYTVR LELPQYTSSD SDVESPYTLI DSLVLMPYCK SLDIFTVGGS GDGVVTNSAW ETFQRYRCLE NSRSVVKTPM TDVCRNIIFS ISALLHQTGL ACECDPQGSL SSVCDPNGG
Highest antigen sequence indentity to the following orthologs: Rat - 96%, Mouse - 96%.
Target Information
Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Laminin B1 chain; laminin beta 1; Laminin subunit beta-1; laminin, beta 1; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta; MGC142015
Gene Aliases: CLM; LAMB1; LIS5
UniProt ID: (Human) P07942
Entrez Gene ID: (Human) 3912
cell adhesion
neuronal-glial interaction involved in cerebral cortex radial glia guided migration
extracellular matrix organization
positive regulation of cell migration
neuron projection development
substrate adhesion-dependent cell spreading
endodermal cell differentiation
odontogenesis
positive regulation of epithelial cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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