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Invitrogen
MCM6 Polyclonal Antibody
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Product Details
PA5-82167
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MCM6. Recombinant protein control fragment (Product #RP-102470).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VILRAEAVES AQAGDKCDFT GTLIVVPDVS KLSTPGARAE TNSRVSGVDG YETEGIRGLR ALGVRDLSYR LVFLACCVAP TNPRFGGKEL RDEEQTAESI KNQMTVKEWE KVFEMSQDKN LYHNLCTSLF PTIHGNDEVK RGV
Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 97%.
Target Information
MCM6 may be involved in the control of a single round of DNA replication during S phase. It binds to chromatin during G1 and detaches from it during S phase as if it licenses the chromatin to replicate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA replication licensing factor MCM6; intestinal DNA replication protein; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe); mini chromosome maintenance deficient 6; minichromosome maintenance deficient (mis5, S. pombe) 6; minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe); Mis5 homolog; p105MCM; unnamed protein product
Gene Aliases: ASP-l1; D1Wsu22e; MCG40308; MCM6; Mcmd6; Mis5; P105MCM
UniProt ID: (Human) Q14566, (Mouse) P97311
Entrez Gene ID: (Human) 4175, (Rat) 29685, (Mouse) 17219
nucleotide binding
DNA binding
DNA helicase activity
single-stranded DNA binding
helicase activity
protein binding
ATP binding
hydrolase activity
ATPase activity
identical protein binding
single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity
ATP-dependent DNA helicase activity
DNA metabolism protein
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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