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Invitrogen
Tenascin C Polyclonal Antibody
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Product Details
PA5-82168
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TNC. Recombinant protein control fragment (Product #RP-102366).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RLVKLIPGVE YLVSIIAMKG FEESEPVSGS FTTALDGPSG LVTANITDSE ALARWQPAIA TVDSYVISYT GEKVPEITRT VSGNTVEYAL TDLEPATEYT LRIFAEKGPQ KSSTITAKFT TDLDSPRDLT ATEV
Highest antigen sequence indentity to the following orthologs: Rat - 86%, Mouse - 84%.
Target Information
Tenascin is a high molecular weight, multifunctional, extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors (Erickson and Bourdon 1989). It has been described under a variety of names: cytotactin, hexabrachion protein, J1, myotendinous antigen (MI) and glioma mesenchymal extracellular matrix (GMEM). The tenascin molecule is a disulfide-linked hexamer. The expression of tenascin is associated with development and growth, both normal and pathological, whereas the distribution in normal adult tissue is restricted.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytotactin; deafness, autosomal dominant 56; Glioma-associated-extracellular matrix antigen; GMEM; GP 150-225; Hexabrachion; hexabrachion (tenascin); JI; MGC144208; MGC144209; MGC167029; Myotendinous antigen; Neuronectin; Tenascin; Tenascin-C; tenascin-C additional domain 1; tenascin-C isoform 14/AD1/16; TN; TN-C
Gene Aliases: 150-225; DFNA56; GMEM; GP; HXB; JI; TN; TN-C; TNC
UniProt ID: (Human) P24821
Entrez Gene ID: (Human) 3371
osteoblast differentiation
cell adhesion
negative regulation of cell adhesion
neuromuscular junction development
positive regulation of cell proliferation
response to wounding
response to mechanical stimulus
positive regulation of gene expression
peripheral nervous system axon regeneration
extracellular matrix organization
wound healing
odontogenesis of dentin-containing tooth
response to ethanol
bud outgrowth involved in lung branching
mesenchymal-epithelial cell signaling involved in prostate gland development
prostate gland epithelium morphogenesis
cellular response to retinoic acid
cellular response to vitamin D
response to fibroblast growth factor
cellular response to prostaglandin D stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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