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Invitrogen
DLX5 Polyclonal Antibody
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Product Details
PA5-82204
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DLX5. Recombinant protein control fragment (Product #RP-102491).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RRVPSIRSGD FQAPFQTSAA MHHPSQESPT LPESSATDSD YYSPTGGAPH GYCSPTSASY GKALNPYQYQ YHGVNGSAGS YPAKAYADYS YASSYHQYGG AYNRVPSATN QPEKEVTEPE VRMVNGKPKK VRKP
Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 92%.
Target Information
This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: distal-less homeo box 5; Homeobox protein DLX-5; split hand/foot malformation type 1 with sensorineural hearing loss
Gene Aliases: DLX5; SHFM1D
UniProt ID: (Human) P56178
Entrez Gene ID: (Human) 1749
skeletal system development
osteoblast differentiation
endochondral ossification
transcription from RNA polymerase II promoter
nervous system development
axon guidance
cell proliferation
embryonic limb morphogenesis
BMP signaling pathway
epithelial cell differentiation
inner ear morphogenesis
positive regulation of osteoblast differentiation
positive regulation of transcription, DNA-templated
anatomical structure formation involved in morphogenesis
positive regulation of epithelial cell proliferation
palate development
olfactory pit development
face morphogenesis
cellular response to BMP stimulus
positive regulation of canonical Wnt signaling pathway
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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