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Invitrogen
Fascin Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-82210
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FSCN1. Recombinant protein control fragment (Product #RP-88616).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.10 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GKDELFALEQ SCAQVVLQAA NERNVSTRQG MDLSANQDEE TDQETFQLEI DRDTKKCAFR THTGKYWTLT ATGGVQSTAS SKNASCYFDI EWRDRRITLR ASNGKFVTSK KNGQ
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 63%.
Target Information
Fascin organizes filamentous actin into bundles with a minimum of 4. 1:1 actin/fascin ratio. It is probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; epididymis secretory sperm binding protein; fascin 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin-bundling protein; fascin-like protein; BLES06; Fascin1; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); singed-like protein; unnamed protein product
Gene Aliases: Fan1; Fascin; fascin-1; HSN; p55; SNL
UniProt ID: (Human) Q16658, (Mouse) Q61553, (Rat) P85845
Entrez Gene ID: (Human) 6624, (Mouse) 14086, (Rat) 683788
actin filament organization
cell-cell junction assembly
establishment or maintenance of cell polarity
positive regulation of lamellipodium assembly
cell migration
microspike assembly
actin cytoskeleton organization
parallel actin filament bundle assembly
regulation of microvillus assembly
regulation of actin cytoskeleton organization
establishment of apical/basal cell polarity
cell motility
actin filament bundle assembly
positive regulation of filopodium assembly
positive regulation of podosome assembly
positive regulation of extracellular matrix disassembly
liver development
cellular response to cell-matrix adhesion
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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