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Invitrogen
TCP-1 epsilon Polyclonal Antibody
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Product Details
PA5-82227
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CCT5. Recombinant protein control fragment (Product #RP-102163).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ALQKYEKEKF EEMIQQIKET GANLAICQWG FDDEANHLLL QNNLPAVRWV GGPEIELIAI ATGGRIVPRF SELTAEKLGF AGLVQEISFG TTKDKMLVIE QCKNSRAVTI FIRGGNKMII EEAKRSLHDA LCVIRNLIRD NRVVYGGGA
Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 97%.
Target Information
This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCT-epsilon; Chaperonin containing T-complex polypeptide 1 subunit 5; chaperonin containing TCP1, subunit 5 (epsilon); chaperonin subunit 5 (epsilon); epididymis secretory protein Li 69; T-complex protein 1 subunit epsilon; TCP-1-epsilon
Gene Aliases: CCT-epsilon; CCT5; CCTE; HEL-S-69; KIAA0098; mKIAA0098; PNAS-102; TCP-1-epsilon; TCPE
UniProt ID: (Human) P48643, (Mouse) P80316, (Rat) Q68FQ0
Entrez Gene ID: (Human) 22948, (Mouse) 12465, (Rat) 294864
protein folding
binding of sperm to zona pellucida
response to virus
positive regulation of telomere maintenance via telomerase
protein stabilization
toxin transport
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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