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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PDALKSRTIR KWNTTLYEGT WRRGSTAGGC RNYPATFWVN PQFKIRLDET DDPDDYGDRE SGCSFVLALM QKHRRRERRF GRDMETIGFA VYEVPPELVG QPAVHLKRDF FLANASRARS EQFINLREVS TRFRLPPGEY VVVPSTFEPN KE
Highest antigen sequence indentity to the following orthologs: Rat - 88%, Mouse - 88%.
The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calcium-activated neutral proteinase 1; Calpain mu-type; Calpain-1 catalytic subunit; Calpain-1 large subunit; Calpain-I; Calpain-II; CANP 1; Cell proliferation-inducing gene 30 protein; Micromolar-calpain; muCANP
Gene Aliases: CANPL1; CAPN1; PIG30
Entrez Gene ID: (Human) 823
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