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Invitrogen
ARPC2 Polyclonal Antibody
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Product Details
PA5-82347
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ARPC2. Recombinant protein control fragment (Product #RP-89526).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TVVFSTVFKD DDDVVIGKVF MQEFKEGRRA SHTAPQVLFS HREPPLELKD TDAAVGDNIG YITFVLFPRH TNASARDNTI NLIHTFRDYL HYHIKCSKAY IHTRMRAKTS DFLKVLNRAR PDAEKKEMKT ITGKTFSSR
Highest antigen sequence indentity to the following orthologs: Mouse - 99%, Rat - 99%.
Target Information
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 34 kD subunit of the Arp2/3 protein complex; actin related protein 2/3 complex, subunit 2, 34kDa; Actin-related protein 2/3 complex subunit 2; actin-related protein 2/3 complex subunit 2 {ECO:0000250|UniProtKB:O15144}; Arp2/3 complex 34 kDa subunit; arp2/3 complex 34 kDa subunit {ECO:0000250|UniProtKB:O15144}; ARP2/3 protein complex subunit 34; arpc2 {ECO:0000250|UniProtKB:O15144}; NB4 apoptosis/differentiation related protein; p34-ARC; p34-ARC {ECO:0000250|UniProtKB:O15144}; testis tissue sperm-binding protein Li 53e; unnamed protein product
Gene Aliases: 2210023N03Rik; 34kDa; ARC34; ARPC2; p34-Arc; PNAS-139; PRO2446
UniProt ID: (Human) O15144, (Mouse) Q9CVB6
Entrez Gene ID: (Human) 10109, (Rat) 301511, (Mouse) 76709
positive regulation of lamellipodium assembly
actin filament polymerization
positive regulation of actin filament polymerization
Arp2/3 complex-mediated actin nucleation
positive regulation of cellular component biogenesis
positive regulation of cellular component organization
actin polymerization-dependent cell motility
positive regulation of substrate adhesion-dependent cell spreading
regulation of actin filament polymerization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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