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Invitrogen
KCNMB3 Polyclonal Antibody
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Product Details
PA5-82533
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KCNMB3. Recombinant protein control fragment (Product #RP-91042).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TCTAIHTDIM DDWLDCAFTC GVHCHGQGKY PCLQVFVNLS HPGQKALLHY NEEAVQINPK CFYTPKCHQD RNDLLNSALD IKEFFDHKNG TPFSCFYSPA SQ
Highest antigen sequence indentity to the following orthologs: Rat - 75%, Mouse - 69%.
Target Information
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: big potassium channel beta subunit 3; BK beta 3; BK channel beta subunit 3; BK channel subunit beta-3; BKbeta3; calcium-activated potassium channel regulatory subunit; Calcium-activated potassium channel subunit beta-3; Calcium-activated potassium channel, subfamily M subunit beta-3; Charybdotoxin receptor subunit beta-3; HBeta3; K(VCA)beta-3; KCNMB3; large conductance, voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit; Maxi K channel subunit beta-3; MaxiK channel beta-subunit 3; potassium channel subfamily M regulatory beta subunit 3; potassium large conductance calcium-activated channel, subfamily M beta member 3; Slo-beta-3; slobeta3 (KCNMB3); unnamed protein product
Gene Aliases: BKBETA3; HBETA3; K(VCA)BETA-3; KCNMB2; KCNMB3; KCNMBL; SLO-BETA-3; SLOBETA3
UniProt ID: (Human) Q9NPA1
Entrez Gene ID: (Human) 27094
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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