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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SDVVEALSEE HMEADGHAAV VFGTVVDIIS RSGEKIPVSV WMKRMRQERR LCCVVVLEPV ERVSTWVAFQ SDGTVTSCDS LFAHLHGYVS GEDVAGQHIT DLIPSVQLPP SGQHIPKNLK IQRSVGRARD GTTFPLSLKL KSQPSSEEAT
Highest antigen sequence indentity to the following orthologs: Rat - 81%, Mouse - 81%.
PASK is an evolutionarily conserved protein present in yeast, flies, and mammals. PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. It is a conserved gene product found in yeast as well as mammals. PASKIN contains two domains (PAS A and PAS B) as well as a serine/threonine kinase domain related to AMP kinases. PASKIN activity leads to decreased carbohydrate storage, as well as increased protein synthesis. PASKIN-dependent phosphorylation inhibits the activity of mammalian glycogen synthase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: OTTMUSP00000024404; PAS domain-containing serine/threonine-protein kinase; PAS-kinase
Gene Aliases: KIAA0135; PASK
Entrez Gene ID: (Human) 23178
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