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          • Primary Antibodies ›
          • ICA1 Antibodies

          Invitrogen

          ICA1 Polyclonal Antibody

          View all (11) ICA1 antibodies

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          Cite ICA1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          ICA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          ICA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          ICA1 Antibody (PA5-82593) in IHC (P)

          Immunohistochemical analysis of ICA1 in human heart muscle using ICA1 Polyclonal Antibody (Product # PA5-82593) shows strong cytoplasmic positivity in myocytes. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ICA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ICA1 Antibody in Western Blot (WB)
          ICA1 Polyclonal Antibody

          Product Details

          PA5-82593

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human ICA1. Recombinant protein control fragment (Product #RP-89518).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2789750

          Product Specific Information

          Immunogen sequence: DELLDMKSEE GACLGPVAGT PEPEGADKDD LLLLSEIFNA SSLEEGEFSK EWAAVFGDGQ VKEPVPTMAL GEPDPKAQTG SGFLPSQLLD QNMKDLQASL QEPAKAASDL TAWFSLFADL DPLSNPDAVG KTDKEHELL

          Highest antigen sequence indentity to the following orthologs: Mouse - 86%, Rat - 84%.

          Target Information

          This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 69 kDa islet cell autoantigen; 69kDa isoform; diabetes mellitus type I autoantigen; ICA69; ICAp69; Islet cell autoantigen 1; islet cell autoantigen 1, 69kDa; Islet cell autoantigen p69; p69; testicular tissue protein Li 162; unnamed protein product

          View more View less

          Gene Aliases: ICA1; ICA69; ICAp69

          View more View less

          UniProt ID: (Human) Q05084

          View more View less

          Entrez Gene ID: (Human) 3382

          View more View less

          Function(s)
          protein binding protein domain specific binding membrane curvature sensor activity
          Process(es)
          neurotransmitter transport regulation of secretion membrane bending
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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