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Invitrogen
DOPA Decarboxylase Polyclonal Antibody
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Product Details
PA5-82597
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DDC. Recombinant protein control fragment (Product #RP-90666).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LETVMMDWLG KMLELPKAFL NEKAGEGGGV IQGSASEATL VALLAARTKV IHRLQAASPE LTQAAIMEKL VAYSSDQAHS SVERAGLIGG VKLKAIPSDG NFAMRASA
Highest antigen sequence indentity to the following orthologs: Mouse - 90%, Rat - 88%.
Target Information
DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AADC; aromatic L-amino acid decarboxylase; Aromatic-L-amino-acid decarboxylase; DDC; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); HGNC:2719
Gene Aliases: AADC; DDC
UniProt ID: (Human) P20711
Entrez Gene ID: (Human) 1644
cellular amino acid metabolic process
circadian rhythm
multicellular organism aging
aminergic neurotransmitter loading into synaptic vesicle
isoquinoline alkaloid metabolic process
cellular response to drug
dopamine biosynthetic process
catecholamine biosynthetic process
serotonin biosynthetic process
indolalkylamine biosynthetic process
response to pyrethroid
phytoalexin metabolic process
cellular response to alkaloid
cellular response to growth factor stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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