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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SETDB1 Antibodies

          Invitrogen

          SETDB1 Polyclonal Antibody

          View all (18) SETDB1 antibodies

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          Cite SETDB1 Polyclonal Antibody

          • Antibody Testing Data (5)
          SETDB1 Antibody in Immunocytochemistry (ICC/IF)
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          SETDB1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          SETDB1 Antibody (PA5-82617) in ICC/IF

          Immunofluorecent analysis of SETDB1 in human cell line A-431 using SETDB1 Polyclonal Antibody (Product # PA5-82617). Staining shows localization to nucleoplasm, plasma membrane and cytosol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SETDB1 Antibody in Immunocytochemistry (ICC/IF)
          SETDB1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SETDB1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SETDB1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SETDB1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SETDB1 Polyclonal Antibody

          Product Details

          PA5-82617

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human SETDB1. Recombinant protein control fragment (Product #RP-91641).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2789774

          Product Specific Information

          Immunogen sequence: KLRFLIFFDD GYASYVTQSE LYPICRPLKK TWEDIEDISC RDFIEEYVTA YPNRPMVLLK SGQLIKTEWE GTWWKSRVEE VDGSLVRILF LDDKRCEWIY RGSTRLEPMF SMKTSSASAL EKKQGQLRTR PNMGAVRSKG PVVQYTQD

          Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 97%.

          Target Information

          This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: ERG-associated protein with a SET domain, ESET; ERG-associated protein with SET domain; ESET; H3-K9-HMTase 4; Histone H3-K9 methyltransferase 4; Histone-lysine N-methyltransferase SETDB1; histone-lysine N-methyltransferase, H3lysine-9 specific 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1; SET domain, bifurcated 1; tudor domain containing 21

          View more View less

          Gene Aliases: ESET; H3-K9-HMTase4; KG1T; KIAA0067; KMT1E; SETDB1; TDRD21

          View more View less

          UniProt ID: (Human) Q15047

          View more View less

          Entrez Gene ID: (Human) 9869

          View more View less

          Function(s)
          DNA binding chromatin binding protein binding zinc ion binding histone-lysine N-methyltransferase activity promoter-specific chromatin binding histone modifying enzyme
          Process(es)
          transcription, DNA-templated Ras protein signal transduction response to vitamin histone lysine methylation response to ethanol positive regulation of methylation-dependent chromatin silencing
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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