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Invitrogen
DUSP26 Polyclonal Antibody
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Product Details
PA5-82621
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DUSP26. Recombinant protein control fragment (Product #RP-91560).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: CPGNWLWASM TFMARFSRSS SRSPVRTRGT LEEMPTVQHP FLNVFELERL LYTGKTACNH ADEVWPGLYL GDQDMANNRR ELRRLGITHV L
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 97%.
Target Information
This gene encodes a member of the tyrosine phosphatase family of proteins and exhibits dual specificity by dephosphorylating tyrosine as well as serine and threonine residues. This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context. This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DSP-4; dual specificity phosphatase 26 (putative); Dual specificity phosphatase SKRP3; Dual specificity protein phosphatase 26; dual-specificity protein phosphatase: MKP8; Low-molecular-mass dual-specificity phosphatase 4; MAP kinase phosphatase 8; MGC1136; MGC2627; Mitogen-activated protein kinase phosphatase 8; NATA1; neuroendocrine-associated phosphatase; Novel amplified gene in thyroid anaplastic cancer; unnamed protein product
Gene Aliases: DSP-4; DUSP24; DUSP26; LDP-4; LDP4; MKP-8; MKP8; NATA1; NEAP; SKRP3
UniProt ID: (Human) Q9BV47
Entrez Gene ID: (Human) 78986
p53 binding
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
protein tyrosine phosphatase activity
protein binding
protein tyrosine/serine/threonine phosphatase activity
hydrolase activity
phosphatase activity
MAP kinase phosphatase activity
RNA polymerase II sequence-specific DNA binding transcription factor binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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