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Invitrogen
TRIM37 Polyclonal Antibody
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TRIM37 Antibody (PA5-82779)
Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of TRIM37 was observed specifically in MCF-7 cells and in SK-MEL-30 cells using anti-TRIM37 Polyclonal Antibody (Product #PA5-82779) in western blot. The relative expression levels of TRIM37 within each cell line is shown using RNA... View More
Product Details
PA5-82779
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TRIM37. Recombinant protein control fragment (Product #RP-93190).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: IHLLDLKDRS SIENLWGLQP RPPASLLQPT ASYSRKDKDQ RKQQAMWRVP SDLKMLKRLK TQMAEVRCMK TDVKNTLSEI KSSSAASGDM QTSLFSADQA ALAACGTENS GRLQDLGMEL LAKSS
Highest antigen sequence indentity to the following orthologs: Mouse - 90%, Rat - 90%.
Target Information
Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1, 4, 5, -trisphosphate (PIP). PI4KB may regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase TRIM37; Mulibrey nanism protein; RING-B-box-coiled-coil protein; RING-type E3 ubiquitin transferase TRIM37; Tripartite motif-containing protein 37
Gene Aliases: KIAA0898; MUL; POB1; TEF3; TRIM37
UniProt ID: (Human) O94972
Entrez Gene ID: (Human) 4591
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of NF-kappaB transcription factor activity
histone H2A monoubiquitination
histone H2A-K119 monoubiquitination
negative regulation of centriole replication
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
protein autoubiquitination
aggresome assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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