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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LRAMNRAALE SGISTKQLTE ADLRRTVEES SRIQRGYGHY FDLCLVNSNL ERTFRELQT
Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 97%.
The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression and signaling. The MAGUK family is divided into four subfamilies: DLG-like, ZO1-like, p55-like and LIN2-like. MPP2 (membrane protein, palmitoylated 2), also known as MAGUK p55 subfamily member 2, discs large homolog 2 or DLG2, is a 576 amino acid protein belonging to the MAGUK family that exists as three alternatively spliced isoforms. MPP2 contains one guanylate kinase-like domain, a PDZ (DHR) domain, two L27 domains and a single SH3 domain. The gene encoding MPP2 maps to the same segment of human chromosome 17 as MPP3, with whom MMP2 likely shares similar function and common structural organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: discs large, homolog 2; membrane palmitoylated protein 2; membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2); unnamed protein product
Gene Aliases: DLG2
UniProt ID: (Human) Q14168
Entrez Gene ID: (Human) 4355
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