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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GNTFLMKPSE RVPGATMLLA KLLQDSGAPD GTLNIIHGQH EAVNFICDHP DIKAISFVGS NKAGEYIFER GSRHGKRVQ
Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 96%.
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: aldehyde dehydrogenase family 6 member A1; aldehyde dehydrogenase family 6, subfamily A1; malonate-semialdehyde dehydrogenase; malonate-semialdehyde dehydrogenase (acetylating); methylmalonate semialdehyde dehydrogenase; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MGC40271; mitochondrial acylating methylmalonate-semialdehyde dehydrogenase; MMSDH; testicular tissue protein Li 122; unnamed protein product
Gene Aliases: 1110038I05Rik; MMSADHA; MMSDH
UniProt ID: (Human) Q02252, (Mouse) Q9EQ20, (Rat) Q02253
Entrez Gene ID: (Human) 4329, (Mouse) 104776, (Rat) 81708
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