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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: IKRNDYQLIC IQDGYLSLLT ETGEVREDLK LPEGELGKEI EGKYNAGEDV QVSVMCAMSE EYAVA
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eIF-5A-2; eIF5AII; translation factor; hypusine-containing protein; eukaryotic initiation factor 5A; unnamed protein product
Gene Aliases: 9630038B20; EIF-5A2; eIF5AII
UniProt ID: (Human) Q9GZV4, (Mouse) Q8BGY2
Entrez Gene ID: (Human) 56648, (Mouse) 208691, (Rat) 310261
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