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Invitrogen
Granzyme H Polyclonal Antibody
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Product Details
PA5-83074
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GZMH. Recombinant protein control fragment (Product #RP-88868).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HPAYNPKNFS NDIMLLQLER KAKWTTAVRP LRLPSSKAQV KPGQLCSVAG WGYVSMSTLA TTLQEVLLTV QKDCQCERLF HGNYSRATEI CVGDPKKTQT GFKGDSGGPL VCKDVAQGIL SYGNKKGTPP GVYIKVSHFL PWIKRTM
Highest antigen sequence indentity to the following orthologs: Mouse - 61%, Rat - 58%.
Target Information
This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alternatively spliced; Cathepsin G-like 2; cathepsin G-like 2, protein h-CCPX; CCP-X; CSP-C; CTSGL2; Cytotoxic serine protease C; Cytotoxic T-lymphocyte proteinase; cytotoxic T-lymphocyte-associated serine esterase 1; cytotoxin serine protease-C; cytotoxin serine protease-C precursor; Granzyme H
Gene Aliases: CCP-X; CGL-2; CGL2; CSP-C; CTLA1; CTSGL2; GZMH
UniProt ID: (Human) P20718
Entrez Gene ID: (Human) 2999
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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