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          • Primary Antibodies ›
          • APEH Antibodies

          Invitrogen

          APEH Polyclonal Antibody

          Advanced Verification
          View all (11) APEH antibodies

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          Cite APEH Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (6)
          • Advanced Verification (1)
          APEH Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          APEH Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          APEH Antibody (PA5-83098) in ICC/IF

          Immunofluorecent analysis of APEH in human cell line U-2 OS using APEH Polyclonal Antibody (Product # PA5-83098). Staining shows localization to cytosol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

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          APEH Antibody in Immunocytochemistry (ICC/IF)
          APEH Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          APEH Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          APEH Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          APEH Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          APEH Antibody in Western Blot (WB)
          APEH Antibody
          APEH Polyclonal Antibody

          Product Details

          PA5-83098

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human APEH. Recombinant protein control fragment (Product #RP-95872).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Amount

          20 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2790254

          Product Specific Information

          Immunogen sequence: IDQDLMVAQF STPSLPPTLK VGFLPSAGKE QSVLWVSLEE AEPIPDIHWG IRVLQPPPEQ ENVQYAGLDF EAILLQPGSP PDKTQVP

          Highest antigen sequence indentity to the following orthologs: Rat - 86%, Mouse - 86%.

          Target Information

          APEH is the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. APEH gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. The protein can play an important role in destroying oxidatively damaged proteins in living cells.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: AARE; Acyl-peptide hydrolase; Acylamino-acid-releasing enzyme; Acylaminoacyl-peptidase; APH; MGC2178; N-acylaminoacyl-peptide hydrolase; OPH; Oxidized protein hydrolase

          View more View less

          Gene Aliases: AARE; ACPH; APEH; APH; D3F15S2; D3S48E; DNF15S2; OPH

          View more View less

          UniProt ID: (Human) P13798

          View more View less

          Entrez Gene ID: (Human) 327

          View more View less

          Function(s)
          RNA binding serine-type endopeptidase activity protein binding peptidase activity serine-type peptidase activity omega peptidase activity hydrolase activity identical protein binding
          Process(es)
          translational termination proteolysis beta-amyloid metabolic process
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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