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Invitrogen
TFB2M Polyclonal Antibody
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Product Details
PA5-83135
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TFB2M. Recombinant protein control fragment (Product #RP-94418).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FKNLGIEAVP WTADIPLKVV GMFPSRGEKR ALWKLAYDLY SCTSIYKFGR IEVNMFIGEK EFQKLMADPG NPDLYHVLSV IWQLACEIK
Highest antigen sequence indentity to the following orthologs: Mouse - 60%, Rat - 64%.
Target Information
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dimethyladenosine transferase 2, mitochondrial; FLJ22661; FLJ23182; h-mtTFB; HCV NS5A-transactivated protein 5; Hepatitis C virus NS5A-transactivated protein 5; Mitochondrial 12S rRNA dimethylase 2; Mitochondrial transcription factor B2; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2; unnamed protein product
Gene Aliases: h-mtTFB; h-mtTFB2; Hkp1; hTFB2M; mtTFB2; NS5ATP5; TFB2M
UniProt ID: (Human) Q9H5Q4
Entrez Gene ID: (Human) 64216
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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