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Invitrogen
SLC11A2 Polyclonal Antibody
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Product Details
PA5-83224
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SLC11A2. Recombinant protein control fragment (Product #RP-95786).
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TNEQVVEVCT NTSSPHAGLF PKDNSTLAVD IYKG
Highest antigen sequence indentity to the following orthologs: Rat - 88%, Mouse - 85%.
Target Information
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dct-1; Divalent cation transporter 1; Divalent metal transporter 1; DMT-1; Natural resistance-associated macrophage protein 2; NRAMP 2; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2; Solute carrier family 11 member 2; unnamed protein product
Gene Aliases: AHMIO1; DCT1; DMT1; NRAMP2; OK/SW-cl.20; SLC11A2
UniProt ID: (Human) P49281
Entrez Gene ID: (Human) 4891
copper ion transmembrane transporter activity
iron ion transmembrane transporter activity
manganese ion transmembrane transporter activity
zinc ion transmembrane transporter activity
protein binding
calcium ion transmembrane transporter activity
cadmium ion transmembrane transporter activity
cobalt ion transmembrane transporter activity
ferrous iron transmembrane transporter activity
lead ion transmembrane transporter activity
nickel cation transmembrane transporter activity
vanadium ion transmembrane transporter activity
symporter activity
solute:proton symporter activity
inorganic cation transmembrane transporter activity
cadmium ion binding
metal ion transmembrane transporter activity
transition metal ion transmembrane transporter activity
chromium ion transmembrane transporter activity
retromer complex binding
response to hypoxia
detection of oxygen
porphyrin-containing compound metabolic process
porphyrin-containing compound biosynthetic process
heme biosynthetic process
ion transport
cobalt ion transport
copper ion transport
iron ion transport
manganese ion transport
cellular iron ion homeostasis
learning or memory
response to iron ion
nickel cation transport
vanadium ion transport
lead ion transport
metal ion transport
cellular manganese ion homeostasis
iron assimilation
cellular response to oxidative stress
iron ion transmembrane transport
copper ion transmembrane transport
nickel cation transmembrane transport
dendrite morphogenesis
erythrocyte development
establishment of localization in cell
transmembrane transport
multicellular organismal iron ion homeostasis
cadmium ion transmembrane transport
manganese ion transmembrane transport
zinc II ion transmembrane transport
hydrogen ion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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