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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KIFDIDEAEE GVKDLKIESD VQEPTEPEDD LDIMLGNKKK KKKNVKFPDE D
Highest antigen sequence indentity to the following orthologs: Rat - 90%, Mouse - 88%.
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eIF2-beta; EIF2BA; EIF2S2; eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa; protein phosphatase 1, regulatory subunit 67; translational initiation factor beta subunit; unnamed protein product
Gene Aliases: eIF-2-beta; EIF2; EIF2B; EIF2beta; PPP1R67
UniProt ID: (Human) P20042
Entrez Gene ID: (Human) 8894
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