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Invitrogen
Calmyrin Polyclonal Antibody
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Product Details
PA5-83608
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CIB1. Recombinant protein control fragment (Product #RP-108356).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SGSRLSKELL AEYQDLTFLT KQEILLAHRR FCELLPQEQR SVESSLRAQV PFEQILSLPE LKANPFKERI CRVFSTSPAK DSLSFEDFLD
Highest antigen sequence indentity to the following orthologs: Rat - 88%, Mouse - 89%.
Target Information
The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining. This protein also interacts with integrin alphabeta, which may implicate this protein as a regulatory molecule for alphabeta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcium and integrin binding 1 (calmyrin); Calcium and integrin-binding protein 1; Calcium- and integrin-binding protein; calcium-binding protein family member; CIB1; Calmyrin; CIB; CIB1; CIBP; DNA-dependent protein kinase interacting protein; DNA-PK interaction protein; DNA-PKcs-interacting protein; Kinase-interacting protein; KIP; SIP2-28; SNK-interacting protein 2-28; testicular secretory protein Li 9
Gene Aliases: CIB; CIB1; CIBP; EV3; KIP; KIP1; PRKDCIP; SIP2-28
UniProt ID: (Human) Q99828
Entrez Gene ID: (Human) 10519
angiogenesis
negative regulation of protein phosphorylation
positive regulation of protein phosphorylation
positive regulation of cell-matrix adhesion
response to ischemia
double-strand break repair
apoptotic process
cellular response to DNA damage stimulus
negative regulation of microtubule depolymerization
endomitotic cell cycle
cell adhesion
spermatogenesis
spermatid development
positive regulation of cell proliferation
negative regulation of cell proliferation
negative regulation of neuron projection development
cell differentiation
platelet formation
positive regulation of cell growth
positive regulation of cell migration
cytoplasmic microtubule organization
positive regulation of cell adhesion mediated by integrin
thrombopoietin-mediated signaling pathway
regulation of cell proliferation
negative regulation of apoptotic process
positive regulation of catalytic activity
negative regulation of megakaryocyte differentiation
positive regulation of NF-kappaB transcription factor activity
cell division
regulation of cell division
negative regulation of protein kinase B signaling
positive regulation of ERK1 and ERK2 cascade
positive regulation of calcineurin-NFAT signaling cascade
cellular response to tumor necrosis factor
cellular response to growth factor stimulus
positive regulation of protein serine/threonine kinase activity
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of protein targeting to membrane
extrinsic apoptotic signaling pathway
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of protein localization to plasma membrane
cellular response to nerve growth factor stimulus
positive regulation of male germ cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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