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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • TRAP1 Antibodies

          Invitrogen

          TRAP1 Polyclonal Antibody

          View all (22) TRAP1 antibodies

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          Cite TRAP1 Polyclonal Antibody

          • Antibody Testing Data (7)
          TRAP1 Antibody in Immunocytochemistry (ICC/IF)
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          TRAP1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          TRAP1 Antibody (PA5-83714) in ICC/IF

          Immunofluorecent analysis of TRAP1 in human cell line MCF7 using TRAP1 Polyclonal Antibody (Product # PA5-83714). Staining shows localization to mitochondria. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          TRAP1 Antibody in Immunocytochemistry (ICC/IF)
          TRAP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TRAP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TRAP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TRAP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TRAP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          TRAP1 Antibody in Western Blot (WB)
          TRAP1 Polyclonal Antibody

          Product Details

          PA5-83714

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human TRAP1. Recombinant protein control fragment (Product #RP-98651).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2790867

          Product Specific Information

          Immunogen sequence: RTTAQLGPRR NPAWSLQAGR LFSTQTAEDK EEPLHSIISS TESVQGSTSK HEFQAETKKL LDIVARSLYS EKEVFIREL

          Highest antigen sequence indentity to the following orthologs: Mouse - 74%, Rat - 71%.

          Target Information

          The 90 kDa heat shock protein (hsp90) family of molecular chaperones is a highly conserved family of proteins that play an important physiological role. Hsp90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of hsp90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like hsp90, TRAP1 is found to be associated with numerous proteins involved in diverse actions. Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting presequence strongly implicates TRAP1 as a mitochondrial matrix protein.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Heat shock protein 75 kDa, mitochondrial; Heat shock protein family C member 5; HSP 75; testicular tissue protein Li 209; TNF receptor-associated protein 1; TNFR-associated protein 1; TRAP-1; Tumor necrosis factor type 1 receptor-associated protein

          View more View less

          Gene Aliases: HSP 75; HSP75; HSP90L; HSPC5; TRAP-1; TRAP1

          View more View less

          UniProt ID: (Human) Q12931

          View more View less

          Entrez Gene ID: (Human) 10131

          View more View less

          Function(s)
          tumor necrosis factor receptor binding protein binding ATP binding protein kinase binding poly(A) RNA binding unfolded protein binding Hsp90 family chaperone
          Process(es)
          response to stress translational attenuation chaperone-mediated protein folding negative regulation of cellular respiration negative regulation of reactive oxygen species biosynthetic process negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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