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Invitrogen
RSF1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-83806
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RSF1. Recombinant protein control fragment (Product #RP-106109).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KYLCECQFDD NLKFKNIINE EDADTMRLQP IGRDKDGLMY WYQLDQDHNV RMYIEEQDDQ DGSSWKCIVR NRNELAETLA LLKAQIDPVL LK
Highest antigen sequence indentity to the following orthologs: Rat - 99%, Mouse - 100%.
Target Information
RSF1 is required for assembly of regular nucleosome arrays by the RSF chromatin remodelling complex. Rsf1 facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappaB transcription activation. Rsf1 represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. Rsf1 interacts with SMARCA5/SNF2H to form the RSF complex and also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HBV pX-associated protein 8; hepatitis B virus x-associated protein; novel transcription coactivator; p325 subunit of RSF chromatin-remodeling complex; PHD-finger nuclear protein XAP8alpha; unnamed protein product
Gene Aliases: HBXAP; p325; RSF-1; XAP8
UniProt ID: (Human) Q96T23
Entrez Gene ID: (Human) 51773
chromatin organization
nucleosome assembly
chromatin remodeling
DNA-templated transcription, initiation
regulation of transcription, DNA-templated
heterochromatin assembly
negative regulation of DNA binding
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of viral transcription
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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