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Invitrogen
GTF2H1 Polyclonal Antibody
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Product Details
PA5-83832
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GTF2H1. Recombinant protein control fragment (Product #RP-102996).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PEGKAKIQLQ LVLHAGDTTN FHFSNESTAV KERDAVKDLL QQLLPKFKRK ANKELEEKNR MLQEDPVLFQ LYKDLVVSQV ISAEEFWANR LNVNATDSSS TSNHKQDVGI SAAFLADVRP QTDGCNGLRY N
Highest antigen sequence indentity to the following orthologs: Rat - 98%, Mouse - 98%.
Target Information
GTF2H1 (general transcription factor IIH, polypeptide 1, 62kDa) is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA. When complexed to CAK, GTF2H1 is involved in RNA transcription by RNA polymerase II.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Basic transcription factor 2 62 kDa subunit; BTF 2; BTF2 p62; BTF2. TFIIH; General transcription factor IIH polypeptide 1; General transcription factor IIH subunit 1; general transcription factor IIH, polypeptide 1, 62kDa; TF2H1; TFIIH basal transcription factor complex p62 subunit
Gene Aliases: BTF2; GTF2H1; P62; TFB1; TFIIH
UniProt ID: (Human) P32780
Entrez Gene ID: (Human) 2965
regulation of cyclin-dependent protein serine/threonine kinase activity
nucleotide-excision repair, DNA duplex unwinding
DNA repair
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
protein phosphorylation
nucleotide-excision repair, DNA incision
positive regulation of transcription from RNA polymerase II promoter
global genome nucleotide-excision repair
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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