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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • NUP50 Antibodies

          Invitrogen

          NUP50 Polyclonal Antibody

          Advanced Verification
          View all (17) NUP50 antibodies

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          Cite NUP50 Polyclonal Antibody

          • Antibody Testing Data (7)
          • Advanced Verification (1)
          NUP50 Antibody in Immunocytochemistry (ICC/IF)
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          NUP50 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          NUP50 Antibody (PA5-83860) in ICC/IF

          Immunofluorecent analysis of NUP50 in human cell line MCF7 using NUP50 Polyclonal Antibody (Product # PA5-83860). Staining shows localization to nucleoplasm and nuclear membrane. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          NUP50 Antibody in Immunocytochemistry (ICC/IF)
          NUP50 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NUP50 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NUP50 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NUP50 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NUP50 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NUP50 Antibody in Western Blot (WB)
          NUP50 Antibody
          NUP50 Polyclonal Antibody

          Product Details

          PA5-83860

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human NUP50. Recombinant protein control fragment (Product #RP-100841).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2791012

          Product Specific Information

          Immunogen sequence: DSQQPSSSGL ASSKACVGNA YHKQLAALDC SVRD

          Highest antigen sequence indentity to the following orthologs: Rat - 71%, Mouse - 76%.

          Target Information

          The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: 50 kDa nucleoporin; CTA-268H5.7; DKFZP564A043; MGC39961; Nuclear pore complex protein Nup50; Nuclear pore-associated protein 60 kDa-like; nuclear pore-associated protein 60L; nucleoporin 50kD; nucleoporin 50kDa; Nucleoporin Nup50; NUP50 protein; OTTHUMP00000199530

          View more View less

          Gene Aliases: NPAP60; NPAP60L; NUP50; PRO1146

          View more View less

          UniProt ID: (Human) Q9UKX7

          View more View less

          Entrez Gene ID: (Human) 10762

          View more View less

          Function(s)
          protein binding Ran GTPase binding scaffold/adaptor protein
          Process(es)
          mRNA export from nucleus tRNA export from nucleus protein import into nucleus mitotic nuclear envelope disassembly regulation of glucose transport viral process protein sumoylation viral transcription gene silencing by RNA intracellular transport of virus regulation of cellular response to heat
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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